An experimental drug protected mice from one of the many ills of our cheeseburger and milkshake-laden Western diet -- non-alcoholic fatty liver disease. The drug reversed liver inflammation, injury and scarring in animals fed a high fat, sugar and cholesterol diet. The diet was designed to replicate the Western fast food diet and recreate the features of non-alcoholic fatty liver disease found in people. The research team plans further testing to move it into human trials.
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How long do batters 'keep their eye on the ball?' Eye and head movements differ when swinging or taking a pitch
Where are baseball batters looking during the fraction of a second when a pitched ball is in their air? Their visual tracking strategies differ depending on whether they're swinging at the pitch, reports a study.
Believing the future will be favorable may prevent action
People tend to believe that others will come around to their point of view over time, according to new findings. The findings show that this 'belief in a favorable future' holds across various contexts and cultures, shedding light on some of the causes and consequences of the political polarization evident today.
New statistical models yield powerful insight from health care databases
Recognizing that administrative health care databases can be a valuable, yet challenging, tool in the nation's ongoing pursuit of personalized medicine, statisticians have developed advanced statistical modeling and analytic tools that can make health care and medical data more meaningful.
Lizard blizzard survivors tell story of natural selection
An unusually cold winter in the US in 2014 took a toll on the green anole lizard, a tree-dwelling creature common to the southeastern United States. A new study offers a rare view of natural selection in this species, showing how the lizard survivors at the southernmost part of their range in Texas came to be more like their cold-adapted counterparts further north.
Scientists link biodiversity genomics with museum wisdom through new public database
A new publicly available database will catalog metadata associated with biologic samples, making it easier for researchers to share and reuse genetic data for environmental and ecological analyses. It links publicly available genetic data to records of where and when samples were collected. Such information is critical for comparing biodiversity in different locations worldwide, across time. Despite calls for more data sharing within the research community, researchers have until now lacked the tools they needed.
Farmers selected maize for agricultural use at high elevations
By analyzing ancient genomes of maize, scientists have found evidence suggesting that eventual agricultural use of the crop throughout the temperate highlands of the US likely occurred due to propagation of varieties with earlier flowering times.
RNAi multiplies its effect in repressing gene expression, structural view suggests
RNAi is a mainstay of contemporary biological research. But how exactly this crucial mechanism functions in humans remains a partial mystery that we are now one step closer to solving. Structural biologists have now published atomic-resolution pictures and a comprehensive analysis of the workings of a part of the RNAi machinery in Molecular Cell. They've discovered how several parts of the machinery work in concert to tamp down gene expression after the attachment of the machinery to an mRNA copied from a gene.
Animal coloration research: On the threshold of a new era
In the last 20 years, the field of animal coloration research has experienced explosive growth thanks to numerous technological advances, and it now stands on the threshold of a new era.
Natural compound coupled with specific gut microbes may prevent severe flu
A particular gut microbe can prevent severe flu infections in mice, likely by breaking down naturally occurring compounds -- called flavonoids -- commonly found in foods such as black tea, red wine and blueberries, new research shows.