In the first prospective ACL reconstruction cohort with over 80 percent follow-up at 10 years, researchers demonstrated that patients could perform sports-related functions and maintain a high knee-related quality of life a decade after surgery, though activity levels decline over time.

People who carry a genetic susceptibility to Alzheimer's disease appear to be at greater risk of diminished cognition from sleep-disordered breathing than those without the susceptibility, according to new research.

A high energy electron in circular/spiral motion radiates vortex photons in the entire wavelength range from the radio-wave to the gamma-rays, researchers have shown theoretically and experimentally. This greatly broadens application spectra of the vortex photons in the field of physical science. Moreover, the finding indicates that vortex photons are ubiquitous in the universe. It paves a way to a completely new research field, natural vortex photon science.

The causes of severe antisocial behavior may differ between boys and girls, which could pave the way for new sex-specific treatments, according to a major new study.

Methicillin-resistant Staphylococcus aureus (MRSA) emerged long before the introduction of the antibiotic methicillin into clinical practice, according to a new study. It was the widespread use of earlier antibiotics such as penicillin rather than of methicillin itself which caused MRSA to emerge, researchers suggest.

A molecular analysis of the mismatch between the tissues of donors and recipients helped predict which recipients required high doses of immune modulating drugs and which needed only low doses.

Scientists have devised a strategy to target cancer cells while sparing normal cells by capitalizing on vulnerabilities that are exposed only in tumor cells. These vulnerabilities are known as the 'Achilles heel' of cancer cells. Although much is known about the mutations that cause a cell to become malignant, little is known about these vulnerabilities.

Among the many factors that impact digital marketing and online advertising strategy, a new study provides insight to a growing trend among firms and big brands: weather-based advertising. According to the study, certain weather conditions are more amenable for consumer responses to mobile marketing efforts, while the tone of your ad content can either help or hurt such response depending on the current local weather.

In 2014, a team of researchers found that clams from the Holocene Epoch (that began 11,700 years ago) contained clues about how sea level rise due to climate change could foreshadow a rise in parasitic trematodes. Now, an international team has found that rising seas could be detrimental to human health on a much shorter time scale.

A gene variant, thought to be carried by nearly 25 percent of the population, increases the odds of developing depression, finds a new study. People with apolipoprotein-E4, called ApoE4 for short, have a 20 percent greater chance of developing clinically significant depressive symptoms later in life compared to those who don't have the gene variant, report the investigators.

Drug-related deaths among middle-aged white men increased more than 25-fold between 1980 and 2014, with the bulk of that spike occurring since the mid-1990s when addictive prescription opioids became broadly available, according to new research.

In addition to the Cas9 protein that bacteria use to bind and snip DNA, bacteria have other Cas proteins that know where to insert that viral DNA into the CRISPR region to remember which viruses have attacked and mount a defense. A research team has discovered how these proteins -- Cas1 and Cas2 -- locate and insert the viral DNA, and it relies on the flexibility of these enzymes and the shape of the DNA.

The unique system of hydraulic control of fins discovered in tuna indicates a new role for the lymphatic system in vertebrates. This natural mechanism may inspire designs for new 'smart' control surfaces with changeable shape and stiffness for both air and underwater unmanned vehicles.

In a discovery that concludes an 80-year quest, researchers found evidence of particles that are their own antiparticles. These 'Majorana fermions' could one day help make quantum computers more robust.

An optical imaging tool has been developed to visualize surface chemistry in real time. Researchers imaged the interfacial chemistry in the microscopically confined geometry of a simple glass micro-capillary. The glass is covered with hydroxyl (-OH) groups that can lose a proton -- a much-studied chemical reaction that is important in geology, chemistry and technology. A 100-micron long capillary displayed a remarkable spread in surface OH bond dissociation constant of a factor of a billion.