One of the key reasons for cancer mortality is caused by the highly invasive behavior of cancer cells, which is often due to aggressive metastasis. Metastasis is facilitated by various growth factors and cytokines secreted from cells of the immune system, which operate through various signaling pathways.

Scientists have described the mechanical principles adopted by liver cells as they remove excess bile during obstructive cholestasis.

Researchers have developed a simple printing method to create effective disease detection tools.

A new study shows that so-called "liquid biopsies", blood tests that detect circulating tumour DNA (ctDNA), may not only sound an early alert that a treatment's effect is diminishing, but may also help explain why -sometimes offering clues about what to do next.

Silver and Douglas firs could replace Norway spruce in the long run due to their greater resistance to droughts.

How do we learn to write? A Japanese study looked at the development of writing skills in Japanese first-grade students, and revealed aspects of handwriting development that have been largely neglected in research carried out in Latin alphabet communities.

"Sport is too much like hard work." For many, that is reason enough to pass when it comes to exercise. But does sport really have to make you break into a sweat? Psychologists have discovered that one's own expectations have a major influence on just how strenuous one perceives a unit of sport to be.

A discovery of how to control and transfer spinning electrons paves the way for novel hybrid devices that could outperform existing semiconductor electronics. Researchers have demonstrated how to combine a commonly used semiconductor with a topological insulator, a recently discovered state of matter with unique electrical properties.

New light has been shed on a misclassified vine species in the Ryukyu Islands of East Asia. This plant was first discovered in 1917 in Taiwan, when it was provisionally identified as Kadsura japonica. The plant was recently spotted again after 100 years, and further investigation proved that it was in fact a different species: Kadsura matsudae.

Illegal fishing, logging and poaching, are impacting two-thirds of the 57 natural World Heritage sites monitored by the International Union for Conservation of Nature this year, putting some of the world's most precious and unique ecosystems and species at risk.

The longitudinal study on children and adolescents is unique worldwide. The study shows that cardiovascular risk factors, such as overweight, high blood pressure, low-density lipoprotein (LDL) cholesterol and insulin resistance, are associated with arterial distensibility in adolescence.

Researchers have further uncovered the secrets of telomeres, the caps that protect the ends of our chromosomes. They discovered that an RNA molecule called TERRA helps to ensure that very short (or broken) telomeres get fixed again. The work provides new insights into cellular processes that regulate cell senescence and survival in aging and cancer.

Chemists have developed a new method to tightly fix catalyst powders on electrode surfaces. Currently, the high physical stress induced on catalyst films by gas evolving reactions hampers the application of powder based catalysts. The developed technique is potentially interesting for hydrogen production by water electrolysis.

Understanding modern biodiversity and extinction threats is important. It is commonly assumed that being large contributes to vulnerability during extinction crises. However, researchers have found that size played no role in the extinction of fish during the largest mass extinction of all time.

While publishers look to produce ever more colourful and exciting texts to entice buyers, University of Sussex psychologists have shown that having more than one illustration per page results in poorer word learning among pre-schoolers.