Статті

Feedback from thousands of designs could transform protein engineering

Лип 13 2017

A large-scale study to test the actual stability of computationally designed proteins shows a way to take some of the guesswork out of protein engineering. Previously, scientists tested only a few tens of proteins, due to prohibitive costs of DNA. This new approach, which incorporates advances in DNA synthesis technology, efficiently checks thousands of mini-protein designs. The hope is that in the future a similar approach could test bigger, more complex, designed proteins.

New imaging technique able to watch molecular dynamics of neurodegenerative diseases

Лип 13 2017

A fast and practical molecular-scale imaging technique has been developed that could let scientists view never-before-seen dynamics of biological processes involved in neurodegenerative diseases such as Alzheimer's disease and multiple sclerosis.

How to cryopreserve fish embryos, bring them back to life

Лип 13 2017

Scientists report for the first time the ability to both deep freeze and reanimate zebrafish embryos. The method could potentially be used to bank larger aquatic and other vertebrate oocytes and embryos, too, for a life in the future.

Ravens can plan ahead, similar to humans and great apes

Лип 13 2017

Despite previous research that indicates such behaviors are unique to humans and great apes, a new study shows that ravens, too, can plan ahead for different types of events , and further, that they are willing to forgo an immediate reward in order to gain a better one in the future.

Yes, the sun is an ordinary, solar-type star after all

Лип 13 2017

The Sun is a solar-type star, a new study claims -- resolving an ongoing controversy about whether the star at the center of our Solar System exhibits the same cyclic behavior as other nearby, solar-type stars.

A neural switch for becoming alpha male

Лип 13 2017

Researchers have identified a neural circuit in the brains of mice that plays a role in social dominance.

Water makes the proton shake

Лип 13 2017

Basic processes in chemistry and biology involve protons in a water environment. Water structures accommodating protons and their motions have so far remained elusive. Applying ultrafast vibrational spectroscopy, researchers map fluctuating proton transfer motions and provide direct evidence that protons in liquid water are predominantly shared by two water molecules. Femtosecond proton elongations within a hydration site are 10 to 50 times faster than proton hopping to a new site, the elementary proton transfer step in chemistry.

Could calcium hold the key to fighting a dangerous hospital infection?

Лип 13 2017

It lurks in hospitals and nursing homes, preying upon patients already weak from disease or advanced age. It kills nearly 30,000 Americans a year, and sickens half a million more. But new research shows that Clostridium difficile bacteria can't do all this without enough of a humble nutrient: calcium. And that new knowledge may lead to better treatment for the most vulnerable patients.

Disease-busting 'recycling bins' in our cells now better understood

Лип 13 2017

Scientists have made an important step in understanding how cells keep themselves clean and healthy -- a finding that may have implications for combating neurodegenerative diseases and cancer.

After 'freezing' in fear, what part of the brain helps make fish swim again?

Лип 13 2017

The brain is the body's mission control center, sending messages to the other organs about how to respond to various external and internal stimuli. Located in the forebrain, the habenular region is one such message-conducting system. Two new papers explain how the habenulae develop and their unsuspected role in recovering from fear.